Kary Mullis

Kary Banks Mullis, Nobel Prize winning chemist, was born on December 28, 1944, in Lenoir, North Carolina.

He received a Bachelor of Science degree in chemistry from the Georgia Institute of Technology in 1966. He earned a Ph.D. degree in biochemistry from the University of California, Berkeley, in 1972 and lectured in biochemistry there until 1973. That year, Kary became a postdoctoral fellow in pediatric cardiology at the University of Kansas Medical School, with emphasis in the areas of angiotensin and pulmonary vascular physiology. In 1977 he began two years of postdoctoral work in pharmaceutical chemistry at the University of California, San Francisco.

Kary joined the Cetus Corporation in Emeryville, California, as a DNA chemist in 1979. During his seven years there, he conducted research on oligonucleotide synthesis and invented the polymerase chain reaction.

Kary received a Nobel Prize in chemistry in 1993, for his invention of the polymerase chain reaction (PCR). The process, which Kary conceptualized in 1983, is hailed as one of the monumental scientific techniques of the twentieth century.

A method of amplifying DNA, PCR multiplies a single, microscopic strand of the genetic material billions of times within hours. The process has multiple applications in medicine, genetics, biotechnology, and forensics. PCR, because of its ability to extract DNA from fossils, is in reality the basis of a new scientific discipline, paleobiology.

Kary has authored several major patents. His patented inventions include the PCR technology and UV-sensitive plastic that changes color in response to light. His most recent patent application covers a revolutionary approach to instantly mobilize the immune system to neutralize invading pathogens and toxins, leading to the formation of his latest venture, Altermune LLC. Altermune is currently focusing on Influenza A and drug resistant Staphylococcus aureus.